4400 centers on the return of 4400 people who, previously presumed dead or reported missing, reappear on Earth. Though they have not aged physically, some of them seem to have deeper alterations ranging from superhuman strength to an unexplained healing touch. A government agency is formed to track the 4400 people after one of them commits a murder.
4400 people, assumed to be dead or missing over the past fifty years, reappear in a ball of light. None have any memory of where they've been, and some are manifesting paranormal …
Tom and Diana investigate a 4400 who has used his ability of enhanced reflexes to become a vigilante.
Tom and Diana investigate Oliver Knox, a 4400 suspected of being a serial murderer.
NTAC races against the clock to stop a group of fanatics targeting 4400s.
Diana helps Tom break Kyle out of NTAC quarantine, eventually leading them to discover the truth behind the 4400.
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